Niharika Konidela is the daughter of actor and producer Nagendra Babu and Padmaja Konidela. She is the niece of actors Chiranjeevi and Pawan Kalyan. Her brother, Varun Tej, and cousins, Ram Charan, Sai Dharam Tej, Vaisshnav Tej, and Allu Arjun are also actors in Telugu cinema. Niharika did her schooling at The Future kids School, Hyderabad and completed her graduation from St. Mary's College, Hyderabad.